Remnants of adenomas in colorectal carcinomas
نویسندگان
چکیده
منابع مشابه
Immunohistochemical Expression of p53 and bcl2 in Colorectal Adenomas and Carcinomas Using Automated Cellular Imaging System
Background & Objective: The current approaches to reduce the risk of colorectal carcinoma are through the detection and removal of the precursor lesion” adenomatous polyps”. The study was conducted to evaluate the immunohistochemical expression of p53 and bcl2 in colorectal adenomas and carcinomas. Patients and Methods: A total of 86 cases, 33 colorectal adenomas, 33 colorect...
متن کاملCharacterization of LGR5 stem cells in colorectal adenomas and carcinomas
LGR5 is known to be a stem cell marker in the murine small intestine and colon, however the localization of LGR5 in human adenoma samples has not been examined in detail, and previous studies have been limited by the lack of specific antibodies. Here we used in situ hybridization to specifically examine LGR5 mRNA expression in a panel of human adenoma and carcinoma samples (n = 66). We found th...
متن کاملimmunohistochemical expression of p53 and bcl2 in colorectal adenomas and carcinomas using automated cellular imaging system
background & objective: the current approaches to reduce the risk of colorectal carcinoma are through the detection and removal of the precursor lesion” adenomatous polyps”. the study was conducted to evaluate the immunohistochemical expression of p53 and bcl2 in colorectal adenomas and carcinomas. patients and methods: a total of 86 cases, 33 colorectal adenomas, 33 colorectal adenocarcin...
متن کاملThe spectrum of p53 mutations in colorectal adenomas differs from that in colorectal carcinomas.
BACKGROUND p53 mutations are frequently observed in colorectal carcinomas but they have also been found in colorectal adenomas, although considerably less frequently. AIMS To explore p53 mutations in benign tumours, we have screened 70 colorectal adenomas for allelic loss at, and point mutations in, TP53 by analysis of selected microdissected cell populations. RESULTS Sixteen (22.8%) adenom...
متن کاملColorectal Adenomas
n engl j med 375;4 nejm.org July 28, 2016 387 from the study if they had received anticoagulant therapy or had undergone carotid revascularization. However, differences aside, the lesson from TIAregistry.org should not be that we have solved the problem of acute recurrent ischemia, but rather that we must redouble our efforts to treat patients before these early recurrent events can occur. In a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer
سال: 1983
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19830515)51:10<1866::aid-cncr2820511019>3.0.co;2-x